LongSafari / text-generation Open weights updated 2 years ago

hyenadna-medium-450k-seqlen-hf

Name: hyenadna-medium-450k-seqlen-hf
Author: LongSafari

Welcome! HyenaDNA is a long-range genomic foundation model pretrained on context lengths of up to 1 million tokens at single nucleotide resolution.

Params

28 M

Context

—

Downloads 30d

179 K

Likes

Commercial use: allowed bsd-3-clause Not gated SAFETENSORS View on Hugging Face ↗

Download history

daily snapshots · 54 days

▲ 0 in the last 30 days (0.0%)

223 K179 K

Sep 18Oct 6Oct 24Nov 10

Can you run it?

Estimated VRAM at 8K context unless noted. Pick your hardware to see the verdict per quantization.

File	Quant	Size	Est. VRAM	Verdict on RTX 4090 · 24 GB
model.safetensors	f32	0.1 GB	0.6 GB	✅ Runs comfortably

Estimate: file size × 1.1 + KV cache at 8K + 0.5 GB overhead. Not a benchmark — how we calculate this.

Run it

copy-paste, exact tags checked against the Hub

~ · curl · api/v1

$ curl -s https://aimodelscomparison.com/api/v1/models/hyenadna-medium-450k-seqlen-hf
{
  "hf_id": "LongSafari/hyenadna-medium-450k-seqlen-hf",
  "params_b": 0.03,
  "context_length": null,
  "license": { "id": "bsd-3-clause", "commercial": "yes" },
  "downloads_30d": 179034,
  "vram_estimates": [
    { "quant": "f32", "gb": 0.6 }
  ],
  "updated_at": "2026-09-18T01:00:38Z"
}

est. VRAM —on RTX 4090 · 24 GBJSON API →

Specifications

Architecture: HyenaDNAForCausalLM
Parameters: 28 M
Tensor type: F32
Vocabulary: 12
Licence: bsd-3-clause
First seen on the Hub: 2023-11-03
Training datasets: undisclosed
Added to our catalog: 2026-09-18

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